Fig. 1
From: Breaking down the evidence for bevacizumab in advanced cervical cancer: past, present and future
Tumor Hypoxia and Viral Oncogenes Drive Angiogenesis. Abbreviations: HPV: Human papillomavirus; pRb: retinoblastoma gene product; HDAC1, 4, 7: Histone deacetylases 1, 4, 7; TSP-1: Thrombospondin-1; HIF-1α: hypoxia-inducible factor 1 alpha; VEGF: Vascular endothelial growth factor